As we reach the end of the first quarter of the 21st century, it is natural to reevaluate scientific and professional achievements as well as the challenges in maintaining and improving the health of the population, including the treatment and rehabilitation of patients. Although difficult, retrospection is necessary, and when done properly, it always brings the necessary strength and quality to considerations regarding innovations. The period behind us was characterized by the consequences of financial and public health disasters, the emergence of new diseases, warfare in our part of the world, migration, social turmoil and re-examination of value systems, a multiple crisis of health workers, computerization and digitalization of society, and an increase in the cost of living, as well as the costs of protecting health and the environment. The period ahead requires from us, as scientists and professionals, behavior and feelings founded in our knowledge, skills, wisdom, and the art of maintaining health achievements and public goods and fairly improving living and working conditions for all people, without exception. In their scientific and professional reflections, the authors of the articles in this issue deal with the achievements and challenges of professionals, which is why we recommend this issue as an interesting source that offers new insights into innovations in medicine and health care.
The author of the letter to the editor, Dr. Mirjana Anđelić, explains the scope of the innovative application of platelet-rich plasma in different conditions in gynecology, emphasizing the necessity of rigorous research into the effectiveness of the application of this method in numerous intrauterine and intraovarian conditions.
Our focus is on the research article of a three-member team, Dr. Bosiljka Đikanović, Dr. Janko Janković, and Dr. Milena Čavić, which delves into the topic of the meaningfulness of population genome screening as an option for early detection of the risk of oncological diseases. Describing the term precise public health, the authors explain that the proper use of artificial intelligence and genome profiling is beneficial provided that, at the same time, efforts are made to eliminate the risk of malignancy and preserve, maintain and build healthy living and working environments.
In an analytical manner, the team of experts led by Dr. Ljubica Dimitrijević as the first author of the original paper, describes the clinical presentation and treatment outcomes in severe conditions with intracerebral bleeding and constructively explains the success of the application of different types of anticoagulants, based on the results of a cohort study conducted in 2024 at the Sveti Sava Special Hospital for Cerebrovascular Diseases.
In her original article, Francisca da Caridade Felix Chitanga, Celina Malaquias critically presents the management of human resources in the Namibe Provincial Hospital “N’Gola Kimbanda”, indicating that workforce shortages, inefficient role distribution, inadequate working conditions, and skill gaps are the main obstacles to health strategies successfully responding to the health needs of the population. In their original article, Dr. Vesna Đorđević et al. describe the application of four new prognostic scoring systems of primary myelofibrosis in examining the correlation between cytogenetics and the degree of bone marrow fibrosis, and provide an assessment of the importance of clinical monitoring of the degree of risk of chromosomal aberrations and the degree of bone marrow fibrosis, in patients with primary myelofibrosis.
In her original article, by presenting a series of cases of doctors from the Western Balkans, Sara Tintor analyzes the physicians’ motivation for emigration from their home countries, their professional status establishment and development in Germany, the German legal system, and overall satisfaction of the physicians.
The review paper by Dr. Predrag Đurđević and Dr. Danijela Jovanović presents in detail the clinical manifestation of a very rare and aggressive form of plasmacytic dyscrasia. Describing the latest therapeutic modalities, the authors highlight the need to continue investing in research and innovating treatment approaches that would yield better outcomes. Zoonoses are among the most common newly discovered diseases. Dr. Dolika D. Vasović et al.
describe a rare case of zoonosis - dirofilariasis of the lower eyelid. Although timely surgical intervention often leads to complete resolution of the condition, complications can arise due to inadequate diagnosis and treatment. The authors additionally point out that dirofilariasis is an endemic disease in Serbia, although it is often associated with trips to Mediterranean countries.
The case report, by Dr. Miljana Vrhovac et al., provides a step-by-step description of the treatment of COVID-19 with the drug casirivimab/indevimab in a patient with an injury to the cervical spine, thus providing the missing insights and answers to the dilemmas faced by health professionals in the previous period.
By presenting a case of peripheral facial nerve paralysis, as a rare manifestation of a neuroendocrine tumor of the middle ear, Dr. Ana Miljković provides an excellent example of the need for integrated health care and multidisciplinary management, in order to improve outcomes and minimize the risks of disease recurrence. This approach begins with the early recognition of symptoms of malignancy at the primary level of health care, and continues at the hospital level encompassing advanced diagnostics and imaging, as well as histopathological confirmation, followed by surgical interventions and adjuvant therapies.
The diversity of the studies described demonstrates the richness of thought and activity in our professional environment and inspires us to contribute to a healthier present and a healthier future. This is why we end our issue with a new call for papers, which we are publishing in its entirety.
Sincerely

